We often think biologically about such questions. Sometimes it is a breakdown within the human body; a heart that has given out or cancer that has overcome.
Sometimes it is an external event that happens to the body which brings about death; a car accident, gunshot wound or a fall off the ladder while cleaning the rain gutter.
A recent report from the American Psychological Association suggests that loneliness and social isolation may be a prime factor in bringing about early death – or at least a death earlier than it needed to be. This becomes a particularly pertinent issue for the elderly, widowed, and suicidal. Especially in a culture that sadly is accepting physician assisted suicide as a means of dying. Read more here.